Ipamorelin
PopularSelective growth hormone secretagogue with minimal side effects
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• Major cities (JHB, CPT, DBN): R195 overnight
• Outlying areas: R275 (2-3 business days)
• Collect in person: Free (Sandton location)
Ipamorelin is a potent, synthetic pentapeptide and a highly selective growth hormone secretagogue receptor (GHSR) agonist. It is designed to stimulate the pulsatile release of endogenous growth hormone (GH). This compound serves as a valuable research tool for investigating the dynamics of the somatotropic axis.
- •Potent and selective GHSR agonism.
- •Stimulates robust growth hormone release.
- •Minimal or negligible impact on cortisol levels.
- •Does not significantly elevate prolactin concentrations.
- •Avoids confounding hormonal side effects seen in earlier GHRPs.
- •Facilitates precise study of GH regulatory mechanisms.
- •High purity suitable for demanding laboratory protocols.
Ipamorelin functions as an agonist at the Growth Hormone Secretagogue Receptor (GHSR), primarily located in the pituitary gland and hypothalamus. Binding to GHSR initiates a signaling cascade, mimicking the action of the endogenous ligand ghrelin, which leads to the release of stored growth hormone from somatotroph cells. Unlike many older GH-releasing peptides, Ipamorelin exhibits high functional selectivity, activating the GHSR without cross-reactivity that would typically stimulate adrenocorticotropic hormone (ACTH) or prolactin release.
Due to its high specificity and favorable hormonal profile, Ipamorelin is extensively utilized in endocrinology and physiology research. It is a critical tool for studying age-related decline in GH output, metabolic regulation, and the precise mechanisms governing GH pulsatility. Furthermore, it is employed in comparative studies to assess the efficacy and safety profile differences between various GH-releasing compounds, providing cleaner data unmasked by concurrent elevations in stress hormones like cortisol.
Based on research applications and synergistic mechanisms, this peptide is frequently combined with:
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CJC-1295 with DAC
Long-acting growth hormone-releasing hormone analog with extended half-life
CJC-1295 without DAC
Shorter-acting GHRH analog providing pulsatile growth hormone release
GHRP-6
CJC-1295 + Ipamorelin Blend
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Research Use Only
This product is sold strictly for research purposes only. It is not approved by the FDA for human consumption or medical use. Intended for laboratory and research applications by qualified researchers and institutions only.